Recombinant Human ERF protein (ab158383)
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Overview
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Product nameRecombinant Human ERF protein
See all ERF proteins and peptides -
Protein lengthProtein fragment
Description
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NatureRecombinant
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SourceWheat germ
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Amino Acid Sequence
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SpeciesHuman
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SequenceLGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPG VFRVYPRPRGGPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPS PTLSPMYPSG
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Amino acids181 to 290
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Tagsproprietary tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab158383 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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FormLiquid
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Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- ERF
- ERF_HUMAN
- ETS domain containing transcription factor ERF
see all -
FunctionPotent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment (By similarity). May be important for regulating trophoblast stem cell differentiation.
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Tissue specificityHighest levels in testis, ovary, pancreas, and heart.
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Sequence similaritiesBelongs to the ETS family.
Contains 1 ETS DNA-binding domain. -
Post-translational
modificationsPhosphorylated by multiple kinases including MAPK1/ERK2 at THR-526. Phosphorylation regulates the activity of ERF. -
Cellular localizationNucleus.
- Information by UniProt
Images
Datasheets and documents
References
ab158383 has not yet been referenced specifically in any publications.