Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAK MLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTI VTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIV IDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHN YVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKV LKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGK YCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQ EKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGS QFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
    • Molecular weight

      75 kDa including tags
    • Amino acids

      1 to 437

Specifications

Our Abpromise guarantee covers the use of ab132376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • Cl1 protein
    • D5S1995
    • ERF
    • eRF1
    • ERF1_HUMAN
    • ETF1
    • Eukaryotic peptide chain release factor subunit 1
    • Eukaryotic release factor 1
    • Eukaryotic translation termination factor 1
    • MGC111066
    • Polypeptide chain release factor 1
    • Protein Cl1
    • RF1
    • Sup45 (yeast omnipotent suppressor 45) homolog like 1
    • SUP45L1
    • TB3 1
    • TB3-1
    see all
  • Function

    Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
  • Sequence similarities

    Belongs to the eukaryotic release factor 1 family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab132376 stained with Coomassie Blue.

References

ab132376 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab132376.
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