Recombinant Human FBXL21 protein (ab161927)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MNVSESHFVSALTVFINSKSLSSIKIEDTPVDDPSLKILVANNSDTLRLL KMSSCPHVSSDDGLHFLKLE
    • Amino acids
      1 to 70
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • F box and leucine rich repeat protein 21
    • F box and leucine rich repeat protein 3 pseudogene
    • F box and leucine rich repeat protein 3B
    • F box protein Fbl3b
    • F box/LRR repeat protein 21
    • F box/LRR repeat protein 3B
    • F-box and leucine-rich repeat protein 21
    • F-box and leucine-rich repeat protein 3B
    • F-box/LRR-repeat protein 21
    • F-box/LRR-repeat protein 3B
    • Fbl 21
    • FBL 3
    • FBL 3B
    • Fbl21
    • FBL3
    • FBL3B
    • FBXL 21
    • FBXL 3B
    • FBXL 3P
    • Fbxl21
    • FBXL3B
    • FBXL3P
    • FXL21_HUMAN
    • MGC120237
    see all
  • Function
    Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian pacemaker function. The SCF(FBXL21) complex acts by mediating ubiquitination and subsequent degradation of CRY1. Probable clock-controlled protein that plays a specific role in suprachiasmatic nucleus, SCN and pacemaker function.
  • Sequence similarities
    Contains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • Information by UniProt

Images

  • ab161927 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161927 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161927.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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