Product nameRecombinant Human FBXL21/FBL3 protein
See all FBXL21/FBL3 proteins and peptides
Protein lengthProtein fragment
Amino Acid Sequence
SequenceVSKVVLGRVGLNCPRLIELVVCANDLQPLDNELICIAEHCTNLTALGLSK CEVSCSAFIRFVRLCERRLTQLSVMEEVLIPDEDYSLDEIHTEVSKYLGR VWFPDVMPLW
Amino acids167 to 276
TagsGST tag N-Terminus
Our Abpromise guarantee covers the use of ab161928 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
This product was previously labelled as FBXL21
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- F box and leucine rich repeat protein 21
- F box and leucine rich repeat protein 3 pseudogene
- F box and leucine rich repeat protein 3B
FunctionSubstrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian pacemaker function. The SCF(FBXL21) complex acts by mediating ubiquitination and subsequent degradation of CRY1. Probable clock-controlled protein that plays a specific role in suprachiasmatic nucleus, SCN and pacemaker function.
Sequence similaritiesContains 1 F-box domain.
Contains 7 LRR (leucine-rich) repeats.
- Information by UniProt
ab161928 has not yet been referenced specifically in any publications.