Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MKRGGRDSDRNSSEEGTAEKSKKLRTTNEHSQTCDWGNLLQDIILQVFKY LPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIK QIIKRHSNHLQYVSFKVDSSKESAEAACDILSQLVNCSLKTLGLISTARP SFMDLPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVANNSDTL KLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHV RLEHLRIDVVSENPGQTHFHTIQKSSWDAFIRHSPKVNLVMYFFLYEEEF DPFFRYEIPATHLYFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEE LIRIAERCKNLSAIGLGECEVSCSAFVEFVKMCGGRLSQLSIMEEVLIPD QKYSLEQIHWEVSKHLGRVWFPDMMPTW
    • Amino acids

      1 to 428
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • F box and leucine rich repeat protein 3
    • F box and leucine rich repeat protein 3A
    • F box protein Fbl3a
    • F-box and leucine-rich repeat protein 3A
    • F-box/LRR-repeat protein 3
    • F-box/LRR-repeat protein 3A
    • FBL3
    • FBL3A
    • Fbxl3
    • FBXL3_HUMAN
    • FBXL3A
    see all
  • Function

    Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Contains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • Cellular localization

    Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt

Images

  • ab161929 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161929 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161929.
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