Description

  • Product name

    Recombinant human FGF20 protein
  • Biological activity

    Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected-ED50-is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105-units/mg.

  • Purity

    > 90 % SDS-PAGE.
    Greater than 90% by SDS-PAGE and HPLC analyses.
  • Endotoxin level

    < 0.100 Eu/µg
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      PLAEVGGFLG GLEGLGQQVG SHFLLPPAGE RPPLLGERRS AAERSARGGP GAAQLAHLHG ILRRRQLYCR TGFHLQILPD GSVQGTRQDH SLFGILEFIS VAVGLVSIRG VDSGLYLGMN DKGELYGSEK LTSECIFREQ FEENWYNTYS SNIYKHGDTG RRYFVALNKD GTPRDGARSK RHQKFTHFLP RPVDPERVPE LYKDLLMYT
    • Predicted molecular weight

      23 kDa
    • Amino acids

      3 to 211

Specifications

Our Abpromise guarantee covers the use of ab50022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.6
    Constituents: 0.3% Tris, 8.7% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in 10mM Tris, pH 7.6, to a concentration of 0.1-1.0 mg/ml. Do not vortex. Store at 2°C to 8°C for 1 week, or prepare for extended storage. For extended storage follow reconstitution with further dilution in a buffer containing a carrier protein (example 0.1% BSA). Store working aliquots at -20°C to -80°C.

General Info

  • Alternative names

    • FGF-20
    • Fgf20
    • FGF20_HUMAN
    • FGFK
    • Fibroblast growth factor 20
    • RHDA2
    see all
  • Function

    Neurotrophic factor that regulates central nervous development and function.
  • Tissue specificity

    Predominantly expressed in the cerebellum.
  • Sequence similarities

    Belongs to the heparin-binding growth factors family.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab50022 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab50022.
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