Product nameRecombinant Human FGFR4 protein
See all FGFR4 proteins and peptides
Protein lengthProtein fragment
Amino Acid Sequence
Our Abpromise guarantee covers the use of ab55761 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity> 90 % SDS-PAGE.
ab55761 purity: > 90%, by SDS-PAGE and visualised by silver stain. Endotoxin level: < 0.1 ng per µg of FGFR4+Fc
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
ReconstitutionThis protein is soluble in water and most aqueous buffers. The lyophilised FGFR4+Fc should be reconstituted in PBS or medium to a concentration not lower than 50 µg/ml.
- CD 334
- CD334 antigen
FunctionReceptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.
Tissue specificityExpressed in gastrointestinal epithelial cells, pancreas, and gastric and pancreatic cancer cell lines.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.
Cellular localizationMembrane. Isoform 2 may be secreted.
- Information by UniProt
ab55761 has not yet been referenced specifically in any publications.