Overview

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      MWLDHRAVSQVNRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICW DKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKGWDDSFWKMIGL EDFVADNYSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAH AGGLGVIGADVRGHGLICEGQPVTSRLAVICGTSSCHMGISKDPIFVPGV WGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSI YAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLK LSQDLDDLAILYLATVQAIALGTRFIIEAMEAAGHSISTLFLCGGLSKNP LFVQMHADITGMPVVLSQEVESVLVGAAVLGACASGDFASVQEAMAKMSK VGKVVFPRLQDKKYYDKKYQVFLKLVEHQKEYLAIMNDD
    • Amino acids

      1 to 439
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • fggy
    • FGGY carbohydrate kinase domain containing
    • FGGY carbohydrate kinase domain-containing protein
    • FGGY_HUMAN
    • FLJ10986
    • MGC94804
    • OTTHUMP00000010078
    • OTTHUMP00000010081
    • OTTHUMP00000010082
    • OTTHUMP00000202071
    • RP11-242B9.1
    see all
  • Tissue specificity

    Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).
  • Involvement in disease

    Defects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS) [MIM:105400]. Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors.
  • Sequence similarities

    Belongs to the FGGY kinase family.
  • Developmental stage

    Expressed in fetal brain (at protein level).
  • Information by UniProt

Images

  • ab163042 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab163042 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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