Description

  • Product name

    Recombinant Human FLJ39155 protein
  • Purity

    > 95 % Purified via His tag.
    Purity determined to be >95% by SDS-PAGE.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      19 kDa
    • Amino acids

      836 to 1009
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • Agrin-like protein
    • AGRINL
    • AGRNL
    • EGF-like
    • EGF-like, fibronectin type III and laminin G domains
    • EGF-like, fibronectin type-III and laminin G-like domain-containing protein
    • EGFLA_HUMAN
    • EGFLAM
    • fibronectin type-III and laminin G-like domain-containing protein
    • FLJ39155
    • Pikachurin
    see all
  • Function

    Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness.
  • Sequence similarities

    Contains 3 EGF-like domains.
    Contains 2 fibronectin type-III domains.
    Contains 3 laminin G-like domains.
  • Post-translational
    modifications

    O-glycosylated; contains chondroitin sulfate and heparan sulfate.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix. Cell junction > synapse. Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals.
  • Information by UniProt

References

ab127851 has not yet been referenced specifically in any publications.

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