Recombinant human Flt3 / CD135 protein (ab42610)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human
    • Molecular weight
      54 kDa

Specifications

Our Abpromise guarantee covers the use of ab42610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Activity: 20 U/mg. One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of tyrosine substrate per minute at pH 7.4 and 30 C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3 uM Na-orthovanadate, 0.5 mM ATP, 30 ug/ml Poly (Glu:Tyr)4:1 substrate, and 4 ug /ml recombinant Flt3.

  • Applications

    Inhibition Assay

  • Form
    Liquid
  • Additional notes
    This protein was expressed in a Baculovirus infected Sf9 cell expression system. Expected molecular weight of 54.2 kDa.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.0462% DTT, 0.395% Tris HCl, 0.05% Tween, 50% Glycerol, 0.58% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CD 135
    • CD135
    • CD135 antigen
    • Fetal liver kinase 2
    • FL cytokine receptor
    • Flk 2
    • Flk2
    • Flt 3
    • FLT-3
    • Flt3
    • FLT3_HUMAN
    • FMS like tyrosine kinase 3
    • Fms related tyrosine kinase 3
    • Fms-like tyrosine kinase 3
    • Growth factor receptor tyrosine kinase type III
    • Ly-72
    • OTTHUMP0000004234
    • Receptor type tyrosine protein kinase FLT3
    • Stem cell tyrosine kinase 1
    • Stk 1
    • STK-1
    • Stk1
    • Tyrosine protein kinase receptor FLT3
    • Tyrosine-protein kinase receptor FLT3
    see all
  • Function
    Receptor for the FL cytokine. Has a tyrosine-protein kinase activity.
  • Tissue specificity
    Bone marrow cells.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 protein kinase domain.
  • Cellular localization
    Membrane.
  • Information by UniProt

References

ab42610 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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