Recombinant human Flt3 / CD135 protein (L610_E611insCSSDNEYFYVDFREYEYDLKWEF-PRENL) (Active) (ab268586)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 70% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human Flt3 / CD135 protein (L610_E611insCSSDNEYFYVDFREYEYDLKWEF-PRENL) (Active)
See all Flt3 / CD135 proteins and peptides -
Biological activity
The specific activity of FLT3-ITD-NPOS was determined to be 12 nmol/min/mg in a kinase assay using MBP substrate.
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Purity
> 70 % SDS-PAGE.
Affinity purified. -
Expression system
Baculovirus infected Sf9 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Molecular weight information
SDS-PAGE molecular weight: ~82kDa -
Amino acids
571 to 993 -
Tags
GST tag N-Terminus -
Additional sequence information
The Flt3 / CD135 mutant has 28 aa CSSDNEYFYVDFREYEYDLKWEF-PRENL insertion between 610aa and 611aa. GenBank: NM_004119
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Description
Recombinant human Flt3 / CD135 protein (Active)
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab268586 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.50
Constituents: 0.79% Tris HCl, 0.87% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- CD 135
- CD135
- CD135 antigen
see all -
Function
Receptor for the FL cytokine. Has a tyrosine-protein kinase activity. -
Tissue specificity
Bone marrow cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab268586 has not yet been referenced specifically in any publications.