Recombinant Human Follistatin protein (ab113866)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      P19883-1
    • Species
      Human
    • Sequence
      MKHHHHHHAS GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCNSI SEDTEEEEED EDQDYSFPIS SILEW
    • Molecular weight
      36 kDa
    • Amino acids
      30 to 344
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.24% Tris, 0.116% Sodium chloride

  • Reconstitution
    Add deionized water (200 µl) to prepare a working stock solution of approximately 0.5 mg/mL

General Info

  • Alternative names
    • Activin binding protein
    • Activin-binding protein
    • Follistatin
    • FS
    • fst
    • FST_HUMAN
    • Human follistatin gene
    see all
  • Function
    Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
  • Tissue specificity
    Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
  • Sequence similarities
    Contains 3 follistatin-like domains.
    Contains 3 Kazal-like domains.
    Contains 1 TB (TGF-beta binding) domain.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Follistatin protein (ab113866)
    SDS-PAGE - Recombinant Human Follistatin protein (ab113866)
    14% SDS-PAGE separation of Human Follistatin
    1. reduced and boiled sample, 5μg/lane
    2. non-reduced and non-boiled sample, 5μg/lane

References

ab113866 has not yet been referenced specifically in any publications.

Publishing research using ab113866? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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1 Review or Q&A

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Please advise regarding Follistatin peptide,

We have a customer who looking after 2mg concentrated peptide. What is your recommendation referring to the following conditions?



Introduction:
Follistatin is a single-chain g...

Read More

We have two products which may be suitable for your customer as the concentration of these two can be influenced on how much water is added to the lyophilised protein:

ab50163 Follistatin protein

https://www.abcam.com/index.html?datas...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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