Overview

Description

  • Nature
    Recombinant
  • Source
    HEK 293 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      TMCSAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQ ELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQ SWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAG ALCRTFESYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPN EEVARFYAAAMH
    • Molecular weight
      26 kDa including tags
    • Amino acids
      17 to 228
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab169056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Endotoxin level
    < 1.000 Eu/µg
  • Purity
    >95% by SDS-PAGE .
    Lyophilized from 0.22 µm filtered solution.
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 95% PBS, 5% Trehalose
    Note: 5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%.

  • Reconstitution
    It is recommended to reconstitute the lyophilized protein in sterile deionized water to a final concentration of 200 ug/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names
    • beta hFR
    • FBP
    • FBP/PL 1
    • FBP2
    • fetal/placental
    • Folate receptor
    • Folate receptor 2
    • folate receptor 2 (fetal)
    • Folate receptor beta
    • Folate receptor, fetal/placental
    • Folbp 2
    • Folbp2
    • Folr2
    • FOLR2_HUMAN
    • FR beta
    • FR P3
    • FR-beta
    • Placental folate binding protein
    • Placental folate-binding protein
    see all
  • Function
    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
  • Tissue specificity
    Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
  • Sequence similarities
    Belongs to the folate receptor family.
  • Post-translational
    modifications
    Eight disulfide bonds are present.
    N-glycosylated.
  • Cellular localization
    Cell membrane. Secreted.
  • Information by UniProt

Images

  • SDS-PAGE analysis of reduced Human Flt3 ligand protein. Stained overnight with Coomassie Blue.

References

ab169056 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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