Recombinant Human FOLR2 protein (ab169056)

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Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level: < 1.000 Eu/µg
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human FOLR2 protein

  • Purity

    > 95 % SDS-PAGE.
    Lyophilized from 0.22 µm filtered solution.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    HEK 293 cells

  • Accession

    P14207-1

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      TMCSAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQ ELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQ SWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAG ALCRTFESYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPN EEVARFYAAAMH Linker(GGGSGGGS)—10*His(HHHHHHHHHH)

    • Predicted molecular weight

      26 kDa including tags

    • Amino acids

      17 to 228

    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab169056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilized
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 95% PBS, 5% Trehalose

    5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%.

  • Reconstitution
    Reconstitute with sterile deionized water to a concentration of 400 µg/ml.

General Info

  • Alternative names

    • beta hFR
    • FBP
    • FBP/PL 1
    • FBP2
    • fetal/placental
    • Folate receptor
    • Folate receptor 2
    • folate receptor 2 (fetal)
    • Folate receptor beta
    • Folate receptor, fetal/placental
    • Folbp 2
    • Folbp2
    • Folr2
    • FOLR2_HUMAN
    • FR beta
    • FR P3
    • FR-beta
    • Placental folate binding protein
    • Placental folate-binding protein
    see all

  • Function

    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.

  • Tissue specificity

    Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.

  • Sequence similarities

    Belongs to the folate receptor family.

  • Post-translational
    modifications

    Eight disulfide bonds are present.
    N-glycosylated.

  • Cellular localization

    Cell membrane. Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human FOLR2 protein (ab169056)
    SDS-PAGE - Recombinant Human FOLR2 protein (ab169056)
    SDS-PAGE analysis of reduced Human Flt3 ligand protein. Stained overnight with Coomassie Blue.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab169056? Please let us know so that we can cite the reference in this datasheet.

ab169056 has not yet been referenced specifically in any publications.

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