Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKF DMKYMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLS VEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDR FTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKT AASWCLHVNNWLQVSFTAKHANKVKVLDAPVPDCLGVHCDFHQGLLSFYN ARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRCLQKRGSA TSSSNTSLT
    • Amino acids
      1 to 309
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Fibronectin type 3 and SPRY (spla, ryanodine) domain containing (with coiled-coil motif) 1
    • Fibronectin type 3 and SPRY domain containing 1
    • Fibronectin type III and SPRY domain containing 1
    • Fibronectin type III and SPRY domain-containing protein 1
    • Fibronectin type III and SPRY domains containing protein 1
    • FSD1
    • FSD1_HUMAN
    • GLFND
    • MGC3213
    • MGC58341
    • Microtubule-associated protein GLFND
    • MID1-related protein 1
    • midline 1-related protein 1
    • MIR1
    • VLP27
    see all
  • Function
    May be involved in microtubule organization and stabilization.
  • Tissue specificity
    Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
  • Sequence similarities
    Contains 1 B30.2/SPRY domain.
    Contains 1 COS domain.
    Contains 1 fibronectin type-III domain.
  • Domain
    B30.2 box contains a microtubule-binding site.
  • Cellular localization
    Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
  • Information by UniProt

Images

  • ab164001 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164001 has not yet been referenced specifically in any publications.

Publishing research using ab164001? Please let us know so that we can cite the reference in this datasheet.

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