Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence 1
    • Species
      Human
    Amino Acid Sequence 2
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab40115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes

    Previously labelled as GABARAPL2. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Preservative: 0.002% Sodium azide
    Constituents: 0.1% Triton-X-100, 0.121% Tris

General Info

  • Alternative names
    • ATG8
    • ATG8C
    • FLC3A
    • GABA(A) receptor-associated protein-like 2
    • Gabarapl2
    • Gamma-aminobutyric acid receptor-associated protein-like 2
    • Ganglioside expression factor 2
    • GATE-16
    • GATE16
    • GBRL2_HUMAN
    • GEF-2
    • GEF2
    • General protein transport factor p16
    • Golgi-associated ATPase enhancer of 16 kDa
    • MAP1 light chain 3-related protein
    see all
  • Function
    Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
  • Tissue specificity
    Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
  • Sequence similarities
    Belongs to the MAP1 LC3 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Golgi apparatus.
  • Information by UniProt

Images

  • SDS-PAGE. Analysis of GABARAPL2 / GATE-16 Recombinant Protein (1ug). 4-20% SDS gel. Coomassie blue staining. Band size approximately 13 kDa.

References

ab40115 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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