Recombinant human galectin 9/Gal-9 protein (Fc Chimera Active) (ab214991)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 5.000 Eu/mg
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Description
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Product name
Recombinant human galectin 9/Gal-9 protein (Fc Chimera Active)
See all galectin 9/Gal-9 proteins and peptides -
Biological activity
Measured by its binding ability in a functional ELISA.
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Purity
> 95 % SDS-PAGE. -
Endotoxin level
< 5.000 Eu/mg -
Expression system
HEK 293 cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
AFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQT GFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDL CFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQPPG VWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILG GLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQI DNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRL RNLPTINRLEVGGDIQLTHVQT -
Predicted molecular weight
70 kDa including tags -
Amino acids
2 to 323 -
Additional sequence information
Fused to the N-terminus of the Fc region of Human IgG1 (AAI05943.1).
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab214991 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
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Form
Lyophilized -
Additional notes
Previously labelled as galectin 9.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Constituent: 100% PBS
Lyophilized from 0.2µm filtered solution.This product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute with 50 µl sterile water. Add 1X PBS to the desired protein concentration.
General Info
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Alternative names
- 36 kDa beta-galactoside-binding lectin
- Ecalectin
- Gal-9
see all -
Function
Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. -
Tissue specificity
Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue. -
Sequence similarities
Contains 2 galectin domains. -
Domain
Contains two homologous but distinct carbohydrate-binding domains. -
Cellular localization
Cytoplasm. Secreted. May also be secreted by a non-classical secretory pathway. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab214991 has not yet been referenced specifically in any publications.