Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MAFSGSQAPY LSPAVPFSGT IQGGLQDGLQ ITVNGTVLSS SGTRFAVNFQ TGFSGNDIAF HFNPRFEDGG YVVCNTRQNG SWGPEERKTH MPFQKGMPFD LCFLVQSSDF KVMVNGILFV QYFHRVPFHR VDTISVNGSV QLSYISFQ
    • Molecular weight

      19 kDa including tags
    • Amino acids

      1 to 148
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab117677 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.
    ab117677 was purified by proprietary chromatographic techniques and filter sterilized.
  • Form

    Liquid
  • Additional notes

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

    Previously labelled as galectin 9. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol

General Info

  • Alternative names

    • 36 kDa beta-galactoside-binding lectin
    • Ecalectin
    • Gal-9
    • galectin 9
    • Galectin-9
    • galectin9
    • HOM HD 21
    • HOMHD21
    • HUAT
    • Lectin galactoside binding soluble 9
    • LEG9_HUMAN
    • LGAL S9
    • LGALS 9
    • Lgals9
    • LGALS9A
    • MGC117375
    • MGC125973
    • MGC125974
    • Tumor antigen HOM-HD-21
    • UAT
    • Urate transporter/channel
    • Urate transporter/channel protein
    see all
  • Function

    Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.
  • Tissue specificity

    Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue.
  • Sequence similarities

    Contains 2 galectin domains.
  • Domain

    Contains two homologous but distinct carbohydrate-binding domains.
  • Cellular localization

    Cytoplasm. Secreted. May also be secreted by a non-classical secretory pathway.
  • Information by UniProt

References

ab117677 has not yet been referenced specifically in any publications.

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