Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, WB, ELISA
Product nameRecombinant Human Gastrin protein
See all Gastrin proteins and peptides
Expression systemWheat germ
Protein lengthFull length protein
SequenceMQRLCVYVLIFALALAAFSEASWKPRSQQPDAPLGTGANRDLELPWLEQQ GPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDFGRRSAEDE N
Predicted molecular weight38 kDa including tags
Amino acids1 to 101
Our Abpromise guarantee covers the use of ab131754 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- Component II
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
Sequence similaritiesBelongs to the gastrin/cholecystokinin family.
modificationsTwo different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab131754 has not yet been referenced specifically in any publications.