Recombinant Human GCHFR protein (ab180307)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: MS, SDS-PAGE
Description
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Product name
Recombinant Human GCHFR protein -
Purity
> 95 % SDS-PAGE.
ab180307 was purified by using conventional chromatography techniques. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMPYLLISTQIRMEVGPTMVGDEQSDPE LMQHLGASKRRALGNNFYEYYVDDPPRIVLDKLERRGFRVLSMTGVGQTL VWCLHKE -
Predicted molecular weight
12 kDa including tags -
Amino acids
1 to 84 -
Tags
His tag N-Terminus -
Additional sequence information
NP_005249
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab180307 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Mass Spectrometry
SDS-PAGE
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Mass spectrometry
MALDI-TOF -
Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 0.88% Sodium chloride, 40% Glycerol (glycerin, glycerine), 0.02% DTT
General Info
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Alternative names
- GCHFR
- GFRP
- GFRP_HUMAN
see all -
Function
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine. -
Tissue specificity
In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level). -
Sequence similarities
Belongs to the GFRP family. -
Cellular localization
Nucleus. Nucleus membrane. Cytoplasm > cytosol. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab180307 has not yet been referenced specifically in any publications.