Recombinant human GDNF Receptor alpha 1/GFRA1 protein (ab167761)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Tags: His tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE, ELISA
Description
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Product name
Recombinant human GDNF Receptor alpha 1/GFRA1 protein
See all GDNF Receptor alpha 1/GFRA1 proteins and peptides -
Biological activity
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GDNF at 1 µg/mL binds ab167761 with an apparent KD <10 nM. -
Purity
> 95 % SDS-PAGE.
ab167761 is lyophilized from 0.22 µm filtered solution. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
HEK 293 cells -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
DRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRS AMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSPYEPV NSRLSDIFRVVPFISVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCT TSVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTI VPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLK ENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEECLKFL NFFKDNTCLKNAIQAFGNGSDVTVWQPAFPVQTTTATTTTALRVKNKPLG PAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNYEKEGLGASS HITTK -
Predicted molecular weight
46 kDa including tags -
Amino acids
25 to 429 -
Tags
His tag C-Terminus
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab167761 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Functional Studies
SDS-PAGE
ELISA
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Form
Lyophilized -
Additional notes
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GDNF at 1 µg/mL binds ab167761 with an apparent KD <10 nM.This product was previously labelled as GDNF Receptor alpha 1
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 94% PBS, 5% TrehaloseThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute with sterile deionized water to a concentration of 400 µg/ml.
General Info
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Alternative names
- GDNF family receptor alpha 1
- GDNF family receptor alpha-1
- GDNF R
see all -
Function
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. -
Sequence similarities
Belongs to the GDNFR family. -
Cellular localization
Cell membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab167761 has not yet been referenced specifically in any publications.