Overview

  • Product name

    Recombinant Human Gemin6/SIP2 protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMSEWMKK GPLEWQDYIY KEVRVTASEK NEYKGWVLTT DPVSANIVLV NFLEDGSMSV TGIMGHAVQT VETMNEGDHR VREKLMHLFT SGDCKAYSPE DLEERKNSLK KWLEKNHIPI TEQGDAPRTL CVAGVLTIDP PYGPENCSSS NEIILSRVQD LIEGHLTASQ
    • Molecular weight

      22 kDa including tags
    • Amino acids

      1 to 167
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 90 % SDS-PAGE.
    ab140556 was purified using conventional chromatography.
  • Form

    Liquid
  • Additional notes

    Previously labelled as Gemin 6. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 30% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • FLJ23459
    • Gem (nuclear organelle) associated protein 6
    • Gem-associated protein 6
    • GEMI6
    • GEMI6_HUMAN
    • Gemin 6
    • Gemin-6
    • Gemin6
    • SIP2
    see all
  • Function

    The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
  • Cellular localization

    Nucleus > nucleoplasm. Nucleus > gem. Cytoplasm. Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab140556 (3µg)

References

ab140556 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140556.
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