Description

  • Product name

    Recombinant Human GGPS1 protein
  • Purity

    > 90 % SDS-PAGE.
    ab100959 was purified using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHHSSGLVPRGSHMEKTQETVQRILLEPYKYLLQLPGKQVRTK LSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAH SIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDI YWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTL GLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHAIWSRPESTQV QNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGG NPELVALVKHLSKMFKEENE
    • Predicted molecular weight

      37 kDa including tags
    • Amino acids

      1 to 300
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab100959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry

    MALDI-TOF
  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol

General Info

  • Alternative names

    • (2E
    • 6E)-farnesyl diphosphate synthase
    • Dimethylallyltranstransferase
    • Farnesyl diphosphate synthase
    • Farnesyltranstransferase
    • Geranylgeranyl diphosphate synthase
    • Geranylgeranyl diphosphate synthase 1
    • Geranylgeranyl pyrophosphate synthase
    • Geranylgeranyl pyrophosphate synthetase
    • Geranyltranstransferase
    • GGPP synthase
    • GGPP synthetase
    • GGPPS
    • GGPPS_HUMAN
    • GGPPS1
    • GGPPSase
    • GGPS1
    • OTTHUMP00000036073
    • OTTHUMP00000216161
    • OTTHUMP00000216163
    • OTTHUMP00000216164
    see all
  • Function

    Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
  • Tissue specificity

    Abundantly expressed in testis. Found in other tissues to a lower extent.
  • Pathway

    Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
    Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
    Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
  • Sequence similarities

    Belongs to the FPP/GGPP synthase family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab100959 at approximately 37kDa (3µg).

References

ab100959 has not yet been referenced specifically in any publications.

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