Recombinant Human GHRHR protein (ab114388)

Submit a review Submit a question

Key features and details

  • Expression system: Wheat germ
  • Suitable for: WB, ELISA, SDS-PAGE

Description

  • Product name

    Recombinant Human GHRHR protein

  • Expression system

    Wheat germ

  • Accession

    Q02643

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      HMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGE WVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEE ESYFSTVKII

    • Predicted molecular weight

      38 kDa including tags

    • Amino acids

      23 to 132

Specifications

Our Abpromise guarantee covers the use of ab114388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • GHRFR
    • GHRH R
    • GHRH receptor
    • Ghrhr
    • GHRHR_HUMAN
    • GHRHRpsv
    • GRF R
    • GRF receptor
    • GRFR
    • Growth hormone releasing factor receptor
    • Growth hormone releasing hormone receptor
    • Growth hormone-releasing factor receptor
    • Growth hormone-releasing hormone receptor
    see all

  • Function

    Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.

  • Tissue specificity

    Pituitary gland.

  • Involvement in disease

    Defects in GHRHR are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human GHRHR protein (ab114388)
    SDS-PAGE - Recombinant Human GHRHR protein (ab114388)
    ab114388 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab114388? Please let us know so that we can cite the reference in this datasheet.

ab114388 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

There are currently no Customer reviews or Questions for ab114388.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com