Overview

  • Product name
    Recombinant Human GHRHR protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
      Q02643
    • Species
      Human
    • Sequence
      HMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGE WVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEE ESYFSTVKII
    • Molecular weight
      38 kDa including tags
    • Amino acids
      23 to 132

Specifications

Our Abpromise guarantee covers the use of ab114388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    ab114388 is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • GHRFR
    • GHRH R
    • GHRH receptor
    • Ghrhr
    • GHRHR_HUMAN
    • GHRHRpsv
    • GRF R
    • GRF receptor
    • GRFR
    • Growth hormone releasing factor receptor
    • Growth hormone releasing hormone receptor
    • Growth hormone-releasing factor receptor
    • Growth hormone-releasing hormone receptor
    see all
  • Function
    Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
  • Tissue specificity
    Pituitary gland.
  • Involvement in disease
    Defects in GHRHR are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 2 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human GHRHR protein (ab114388)
    SDS-PAGE - Recombinant Human GHRHR protein (ab114388)
    ab114388 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References

ab114388 has not yet been referenced specifically in any publications.

Publishing research using ab114388? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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