Recombinant Human GINS2 protein (ab182799)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: T7 tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human GINS2 protein -
Purity
> 90 % SDS-PAGE.
ab182799 is expressed in E.coli as inclusion bodies. The final product was refolded and chromatographically purified. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MASMTGGQQMGRGEFGSMDAAEVEFLAEKELVTIIPNFSLDKIYLIGGDL GPFNPGLPVEVPLWLAINLKQRQKCRLLPPEWMDVEKLEKMRDHERKEET FTPMPSPYYMELTKLLLNHASDNIPKADEIRTLVKDMWDTRIAKLRVSAD SFVRQQEAHAKLDNLTLMEINTSGTFLTQALNHMYKLRTNLQPLESTQSQ DF -
Predicted molecular weight
23 kDa including tags -
Amino acids
1 to 185 -
Tags
T7 tag N-Terminus -
Additional sequence information
Mature protein; 17 aa N-terminal T7 tag. NP_057179.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab182799 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
This product was previously labelled as PSF2
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituent: 0.32% Tris HCl
Buffer also contains NaCl, KCl, EDTA, arginine, DTT and Glycerol.
General Info
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Alternative names
- DNA replication complex GINS protein PSF2
- GINS complex subunit 2
- GINS complex subunit 2 (Psf2 homolog)
see all -
Function
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. -
Sequence similarities
Belongs to the GINS2/PSF2 family. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localization
Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab182799 has not yet been referenced specifically in any publications.