Overview

  • Product name
    Recombinant Human GLUT10 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      SGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILSTAKKT KPHPRSGD
    • Amino acids
      325 to 382
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.

    Previously labelled as Glucose Transporter GLUT10. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • AA450473
    • ATS
    • facilitated glucose transporter member 10
    • Glucose Transporter GLUT10
    • Glucose transporter type 10
    • glut 10
    • GLUT-10
    • GLUT10
    • GTR10_HUMAN
    • MGC126706
    • slc2a10
    • Solute carrier family 2
    • Solute carrier family 2 member 10
    • Solute carrier family 2, facilitated glucose transporter member 10
    see all
  • Function
    Facilitative glucose transporter.
  • Tissue specificity
    Widely expressed; highest levels in liver and pancreas.
  • Involvement in disease
    Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
  • Sequence similarities
    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Cellular localization
    Endomembrane system. Cytoplasm > perinuclear region.
  • Information by UniProt

Images

  • ab164312 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164312 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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