Recombinant Human Glutaredoxin 1 protein (ab86987)

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Western blot - Recombinant Human Glutaredoxin 1 protein (ab86987)
  • SDS-PAGE - Recombinant Human Glutaredoxin 1 protein (ab86987)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Suitable for: WB, SDS-PAGE

Description

  • Product name

    Recombinant Human Glutaredoxin 1 protein
    See all Glutaredoxin 1 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAQEFVNCKI QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ

Associated products

Specifications

Our Abpromise guarantee covers the use of ab86987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine)

General Info

  • Alternative names

    • GLRX
    • Glrx1
    • GLRX1_HUMAN
    • Glutaredoxin
    • Glutaredoxin-1
    • Glutaredoxin1
    • Grx
    • Grx 1
    • Grx1
    • MGC117407
    • Thioltransferase
    • Thioltransferase 1
    • Thioltransferase-1
    • Thioltransferase1
    • TTase
    • TTase 1
    • TTase-1
    • TTase1
    see all

  • Function

    Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

  • Sequence similarities

    Belongs to the glutaredoxin family.
    Contains 1 glutaredoxin domain.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • Western blot - Recombinant Human Glutaredoxin 1 protein (ab86987)
    Western blot - Recombinant Human Glutaredoxin 1 protein (ab86987)
  • SDS-PAGE - Recombinant Human Glutaredoxin 1 protein (ab86987)
    SDS-PAGE - Recombinant Human Glutaredoxin 1 protein (ab86987)

    15% SDS-PAGE showing ab86987 at approximately 11.7kDa (3µg).

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (1)

Publishing research using ab86987? Please let us know so that we can cite the reference in this datasheet.

ab86987 has been referenced in 1 publication.

  • Ye Q  et al. Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. Cell Chem Biol 26:366-377.e12 (2019). PubMed: 30661989

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