Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
Product nameRecombinant human Glutathione Reductase protein
See all Glutathione Reductase proteins and peptides
Biological activitySpecific activity: > 29 units/ml. One unit will reduce 1.0 µmol of oxidized glutathione per minute at pH 7.5 at 25°C.
Purity> 95 % SDS-PAGE.
Expression systemEscherichia coli
Protein lengthFull length protein
SequenceMGSSHHHHHHSSGLVPRGSHMGSMAMACRQEPQPQGPPPAAGAVASYDYL VIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAV HSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIE IIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLG ITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLR SFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLP VMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVK GIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSH PPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCA NKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL VTLR
Predicted molecular weight54 kDa including tags
Amino acids43 to 522
TagsHis tag N-Terminus
- Anti-Glutathione Reductase antibody [EPR7238] (ab124995)
- Anti-Glutathione Reductase antibody [EPR7237] (ab128933)
- Anti-Glutathione Reductase antibody (ab134315)
- Anti-Glutathione Reductase antibody (ab137513)
- Anti-6X His tag® antibody [HIS.H8] (ab18184)
- Anti-6X His tag® antibody [4D11] (ab5000)
- Anti-Glutathione Reductase antibody (ab87330)
- Anti-6X His tag® antibody (ab9108)
Our Abpromise guarantee covers the use of ab167979 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Glutathione reductase
FunctionMaintains high levels of reduced glutathione in the cytosol.
Sequence similaritiesBelongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
DomainEach subunit can be divided into 4 domains that are consecutive along the polypeptide chain. Domains 1 and 2 bind FAD and NADPH, respectively. Domain 4 forms the interface.
Cellular localizationCytoplasm and Mitochondrion.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab167979 has not yet been referenced specifically in any publications.