Recombinant human GM-CSF protein (Animal Free) (ab217442)

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Description

  • Product name

    Recombinant human GM-CSF protein (Animal Free)
    See all GM-CSF proteins and peptides

  • Biological activity

    The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

  • Purity

    > 98 % SDS-PAGE.
    > 98 % HPLC.

  • Expression system

    Escherichia coli

  • Accession

    P04141

  • Protein length

    Full length protein

  • Animal free

    Yes

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

    • Predicted molecular weight

      15 kDa

    • Amino acids

      18 to 144

    • Additional sequence information

      This product is for the mature full length globular protein containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

Specifications

Our Abpromise guarantee covers the use of ab217442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    For lot specific reconstitution information please contact our Scientific Support Team.

General Info

  • Alternative names

    • Colony stimulating factor
    • Colony Stimulating Factor 2
    • Colony stimulating factor 2 (granulocyte-macrophage)
    • Colony-stimulating factor
    • CSF
    • CSF 2
    • CSF2
    • CSF2_HUMAN
    • GM-CSF
    • GMCSF
    • Granulocyte Macrophage Colony Stimulating Factor
    • Granulocyte-macrophage colony-stimulating factor
    • MGC131935
    • MGC138897
    • MGI1GM
    • Molgramostin
    • Pluripoietin-a
    • Sargramostim
    see all

  • Function

    Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

  • Sequence similarities

    Belongs to the GM-CSF family.

  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab217442 has not yet been referenced specifically in any publications.

Publishing research using ab217442? Please let us know so that we can cite the reference in this datasheet.

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