Name: Recombinant Human GNLY/Granulysin protein
SKU: ab175462

Product name

Recombinant Human GNLY/Granulysin protein
See all GNLY/Granulysin proteins and peptides
Protein length

Full length protein

Our Abpromise guarantee covers the use of ab175462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Stability and Storage

Shipped at Room Temperature. Store at +4°C short term (1-2 weeks). Store at -80°C. Avoid freeze / thaw cycle.

Information available upon request.
Reconstitution

Add 200 µl of deionized water to prepare a working stock solution of 0.5 mg/mL.

Alternative names
- 519
- D2S69E
- GNLY
- GNLY_HUMAN
- Granulysin
- Granulysin precursor
- LAG 2
- LAG2
- Lymphocyte activation gene 2
- Lymphokine LAG 2
- Lymphokine LAG-2
- NKG 5
- NKG5
- Protein NKG5
- T cell activation protein 519
- T lymphocyte activation gene 519
- T-cell activation protein 519
- TLA519
see all
Function

Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.
Tissue specificity

Expressed in natural killer and T-cells.
Sequence similarities

Contains 1 saposin B-type domain.
Post-translational
modifications

A 9 kDa form is produced by proteolytic processing of a 15 kDa protein.
Cellular localization

Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.
Target information above from: UniProt accession P22749 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Human GNLY/Granulysin protein (ab175462)

14% SDS-PAGE analysis of ab175462
Lane 1: reduced and heated sample (2.5 μg)
Lane 2: non-reduced and non-heated sample (2.5 μg)

ab175462 has not yet been referenced specifically in any publications.

Publishing research using ab175462? Please let us know so that we can cite the reference in this datasheet.

Recombinant Human GNLY/Granulysin protein (ab175462)

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