The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab79190 is purified using conventional chromatography techniques.
Endotoxin Level: < 1.0 EU per 1µg of protein (determined by LAL method)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.242% Tris, 20% Glycerol
Epididymis secretory sperm binding protein Li 182mP
Glycine N methyltransferase
HEL S 182mP
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Abundant in liver.
Involvement in disease
Defects in GNMT are the cause of glycine N-methyltransferase deficiency (GNMT deficiency) [MIM:606664]; also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
Belongs to the glycine N-methyltransferase family.