Overview

  • Product name
    Recombinant Human GPCR HM74 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MNRHHLQDHFLEIDKKNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALW IFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDWKFGDIPC RLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCL LWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLP LGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVV RIHIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS FPNFFSTLINRCLQRKITGEPDNNRSTSVELTGDPNKTRGAPEALMANSG EPWSPSYLGPTSNNHSKKGHCHQEPASLEKQLGCCIE
    • Amino acids
      1 to 387
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • G protein coupled receptor 109B
    • G protein coupled receptor HM74
    • G protein coupled receptor HM74B
    • G-protein coupled receptor 109B
    • G-protein coupled receptor HM74
    • G-protein coupled receptor HM74B
    • GPR109B
    • HCA3
    • HCAR3
    • HCAR3_HUMAN
    • HM74
    • HM74B
    • Hydroxycarboxylic acid receptor 3
    • Niacin receptor 2
    • NIACR2
    • Nicotinic acid receptor 2
    • Puma g
    • PUMAG
    see all
  • Function
    Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.
  • Tissue specificity
    Expression largely restricted to adipose tissue and spleen.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Images

  • ab160220 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160220 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab160220.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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