Description

  • Product name

    Recombinant human GRK3 protein
  • Biological activity

    The specific activity of ab131701 was determined to be 6 nmol/min/mg
  • Purity

    > 95 % SDS-PAGE.
    Assessed by densitometry.
  • Expression system

    Baculovirus infected Sf9 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Predicted molecular weight

      84 kDa including tags
    • Amino acids

      1 to 554
    • Tags

      GST tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab131701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    Western blot

  • Form

    Liquid
  • Additional notes

    ab204859 (GRKtide peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.005% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • ADRBK2
    • Adrenergic, beta, receptor kinase 2
    • ARBK2_HUMAN
    • BARK2
    • Beta adrenergic receptor kinase 2
    • Beta ARK 2
    • Beta-adrenergic receptor kinase 2
    • Beta-ARK-2
    • EC 2.7.11.15
    • G protein coupled receptor kinase 3
    • G-protein-coupled receptor kinase 3
    • GRK3
    see all
  • Function

    Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
  • Sequence similarities

    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 PH domain.
    Contains 1 protein kinase domain.
    Contains 1 RGS domain.
  • Information by UniProt

Images

  • The specific activity of GRK3 (ab131701) was determined to be 7 nmol/min/mg as per activity assay protocol
  • SDS PAGE analysis of ab131701
  • SDS PAGE analysis of ab131701
  • The specific activity of ab131701 was determined to be 6 nmol/min/mg.
  • The purity of ab131701 was determined to be >95% by densitometry.

References

ab131701 has not yet been referenced specifically in any publications.

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