Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
      Q8WTQ7
    • Species
      Human
    • Molecular weight
      89 kDa including tags

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity was determined to be 2.5 nmol/min/mg
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    Assessed by densitometry.
  • Form
    Liquid
  • Additional notes

    ab204876 (Cdc25C peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • G protein coupled receptor kinase 7
    • G protein coupled receptor kinase GRK7
    • G protein-coupled receptor kinase 7
    • G protein-coupled receptor kinase GRK7
    • GPRK 7
    • GPRK7
    • GRK 7
    • GRK7
    • GRK7_HUMAN
    see all
  • Function
    Phosphorylates cone opsins thereby initiating their deactivation.
  • Tissue specificity
    Retina. Cones and rod.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
    Contains 1 RGS domain.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • Functional Studies - Recombinant human GRK7 protein (ab125599)
    Functional Studies - Recombinant human GRK7 protein (ab125599)
  • SDS-PAGE - Recombinant human GRK7 protein (ab125599)
    SDS-PAGE - Recombinant human GRK7 protein (ab125599)
    SDS page analysis of ab125599

References

ab125599 has not yet been referenced specifically in any publications.

Publishing research using ab125599? Please let us know so that we can cite the reference in this datasheet.

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