Product nameRecombinant human GSK3 alpha protein
See all GSK3 alpha proteins and peptides
Protein lengthFull length protein
SourceBaculovirus infected Sf9 cells
Amino Acid Sequence
TagsGST tag N-Terminus
Our Abpromise guarantee covers the use of ab42597 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity700 U/mg. One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of glycogen synthase peptide 2 substrate per minute at pH 7.4 and 30C. Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3uM Na-orthovanadate, 0.1 mM ATP, 20 uM substrate, and 0.1 ug recombinant GSK3 alpha.
Additional notesExpressed in a Baculovirus infected Sf9 cell expression system.
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Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.307% Glutathione, 0.0462% DTT, 0.395% Tris HCl, 0.05% Tween, 50% Glycerol, 0.58% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Glycogen synthase kinase 3 alpha
- Glycogen synthase kinase-3 alpha
FunctionImplicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.
Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Contains 1 protein kinase domain.
- Information by UniProt
ab42597 has not yet been referenced specifically in any publications.