Overview

  • Product name

    Recombinant Human GULP protein
  • Protein length

    Full length protein

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMNRAFSR KKDKTWMHTP EALSKHFIPY NAKFLGSTEV EQPKGTEVVR DAVRKLKFAR HIKKSEGQKI PKVELQISIY GVKILEPKTK EVQHNCQLHR ISFCADDKTD KRIFTFICKD SESNKHLCYV FDSEKCAEEI TLTIGQAFDL AYRKFLESGG KDVETRKQIA GLQKRIQDLE TENMELKNKV QDLENQLRIT QVSAPPAGSM TPKSPSTDIF DMIPFSPISH QSSMPTRNGT QPPPVPSRST EIKRDLFGAE PFDPFNCGAA DFPPDIQSKL DEMQEGFKMG LTLEGTVFCL DPLDSRC
    • Molecular weight

      37 kDa including tags
    • Amino acids

      1 to 304
    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab140546 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry

    MALDI-TOF
  • Purity

    > 95 % SDS-PAGE.
    ab140546 is purified using conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

    Previously labelled as CED6. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 50% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names

    • CED6
    • Cell death protein 6 homolog
    • Engulfment adapter protein
    • Engulfment adaptor PTB domain containing 1
    • GULP
    • GULP, engulfment adaptor PTB domain containing 1
    • GULP1
    • GULP1_HUMAN
    • Protein GULP
    • PTB domain adapter protein CED 6
    • PTB domain adapter protein CED-6
    • PTB domain adaptor protein CED6
    • PTB domain-containing engulfment adapter protein 1
    see all
  • Function

    May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
  • Tissue specificity

    Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
  • Sequence similarities

    Belongs to the ced-6 family.
    Contains 1 PID domain.
  • Cellular localization

    Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab140546 (3µg).

References

ab140546 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140546.
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