Recombinant Human HCN4 protein (ab160767)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant Human HCN4 protein -
Expression system
Wheat germ -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
SPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAIPGQHVTLPR KTSSGSLPPPLSLFGARATSSGGPPLTAGPQREPGARPEPVRSKLPSNL -
Amino acids
1105 to 1203 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab160767 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- HCN 4
- Hyperpolarization activated cyclic nucleotide gated potassium channel 4
- Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 4
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Relevance
HCN4 is a member of the family of hyperpolarization activated and cyclic nucleotide gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node. -
Cellular localization
Membrane; multi pass membrane protein.
Images
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SDS-PAGE - Recombinant Human HCN4 protein (ab160767)ab160767 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Datasheets and documents
References
ab160767 has not yet been referenced specifically in any publications.
