Description

  • Product name

    Recombinant human HDAC10 protein
    See all HDAC10 proteins and peptides
  • Biological activity

    Specific Activity: 1.6 pmol/min/ug. Assay condition : 25 mM Tris/Cl, pH8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, and 0.1 mg/ml BSA, 20 uM BPS HDAC substrate, and 20 ng/ul HDAC10. Incubation condition: 30 min at 37ºC.
  • Expression system

    Baculovirus
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Amino acids

      1 to 481
    • Tags

      His tag C-Terminus , GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab80283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.395% Tris HCl, 0.05% Tween, 50% Glycerol, 0.58% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • DKFZP761B039
    • HD 10
    • HD10
    • HDA10_HUMAN
    • HDAC 10
    • Hdac10
    • Histone deacetylase 10
    • MGC149722
    • OTTHUMP00000028555
    see all
  • Function

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  • Tissue specificity

    Ubiquitous. High expression in liver, spleen, pancreas and kidney.
  • Sequence similarities

    Belongs to the histone deacetylase family. HD type 2 subfamily.
  • Cellular localization

    Cytoplasm. Nucleus. Excluded from the nucleoli.
  • Information by UniProt

Images

  • Image showing specific activity of ab80283.
  • SDS-PAGE showing ab80283 at approximately 79kDa (4µg).

References

ab80283 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab80283.
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