Key features and details
- Expression system: Baculovirus
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Product nameRecombinant human HDAC11/HD11 protein
See all HDAC11/HD11 proteins and peptides
Specific Activity: 1.2 pmol/min/ug. Assay condition : 25 mM Tris/Cl, pH8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, and 0.1 mg/ml BSA, 20 uM BPS HDAC substrate, and 40 ng/ul HDAC11 / HD11. Incubation condition: 60 min at 37ºC.
Protein lengthFull length protein
Our Abpromise guarantee covers the use of ab80281 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Previously labelled as HDAC11.
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Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.395% Tris HCl, 0.05% Tween, 50% Glycerol, 0.58% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- HD 11
FunctionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Tissue specificityWeakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
Sequence similaritiesBelongs to the histone deacetylase family.
Cellular localizationNucleus. Predominantly nuclear.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab80281 has not yet been referenced specifically in any publications.