Recombinant Human HDGF protein (ab173057)

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Description

  • Product name

    Recombinant Human HDGF protein
    See all HDGF proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    The purity of ab173057 is greater than 95% ,as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as an 0.2 µM filtered solution.

  • Endotoxin level

    < 1.000 Eu/µg

  • Expression system

    Escherichia coli

  • Accession

    P51858

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFF GTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGY

    • Predicted molecular weight

      13 kDa including tags

    • Amino acids

      1 to 100

    • Tags

      His tag C-Terminus

    • Additional sequence information

      Sequence for the tag: LEHHHHHH

Specifications

Our Abpromise guarantee covers the use of ab173057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.5
    Constituents: 0.24% Tris, 0.03% EDTA, 0.02% DTT

General Info

  • Alternative names

    • FLJ96580
    • HDGF
    • HDGF_HUMAN
    • Hepatoma derived growth factor
    • Hepatoma-derived growth factor
    • High mobility group protein 1 like 2
    • High mobility group protein 1-like 2
    • HMG-1L2
    • HMG1L2
    see all

  • Function

    Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.

  • Tissue specificity

    Ubiquitous.

  • Sequence similarities

    Belongs to the HDGF family.
    Contains 1 PWWP domain.

  • Domain

    The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.

  • Post-translational
    modifications

    Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.

  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab173057 has not yet been referenced specifically in any publications.

Publishing research using ab173057? Please let us know so that we can cite the reference in this datasheet.

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