Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      P51858
    • Species
      Human
    • Sequence
      MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFF GTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGY
    • Molecular weight
      13 kDa including tags
    • Amino acids
      1 to 100
    • Tags
      His tag C-Terminus
    • Additional sequence information
      Sequence for the tag: LEHHHHHH

Specifications

Our Abpromise guarantee covers the use of ab173057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    SDS-PAGE

  • Endotoxin level
    < 1.000 Eu/µg
  • Purity
    >95% by SDS-PAGE .
    The purity of ab173057 is greater than 95% ,as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as an 0.2 µM filtered solution.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.5
    Constituents: 0.24% Tris, 0.03% EDTA, 0.02% DTT

General Info

  • Alternative names
    • FLJ96580
    • HDGF
    • HDGF_HUMAN
    • Hepatoma derived growth factor
    • Hepatoma-derived growth factor
    • High mobility group protein 1 like 2
    • High mobility group protein 1-like 2
    • HMG-1L2
    • HMG1L2
    see all
  • Function
    Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the HDGF family.
    Contains 1 PWWP domain.
  • Domain
    The PWWP domain harbors the heparin-binding sites and is responsible for DNA-binding, while the C-terminal region is essentially unstructured.
  • Post-translational
    modifications
    Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

References

ab173057 has not yet been referenced specifically in any publications.

Publishing research using ab173057? Please let us know so that we can cite the reference in this datasheet.

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