Description

  • Product name

    Recombinant Human HECTD3 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MEGMDKETFEFKFGKELTFTTVLSDQQVVELIPGGAGIVVGYGDRSRFIQ LVQKARLEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTV DALRKLTRFEDFEPSDSRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPAR IYIYPDKLGYETTDALPESSTCSSTLFLPHYASAKVCEEKLRYAAYNCVA IDTDMSPWEE
    • Amino acids

      1 to 210
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab164063 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • E3 ubiquitin-protein ligase HECTD3
    • HECD3_HUMAN
    • HECT
    • HECT domain containing protein 3
    • HECT domain-containing protein 3
    • HECTD3
    • Probable E3 ubiquitin protein ligase HECTD3
    see all
  • Function

    E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Contains 1 DOC domain.
    Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
  • Cellular localization

    Cytoplasm > perinuclear region.
  • Information by UniProt

Images

  • ab164063 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab164063 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab164063.
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