Overview

  • Product name

    Recombinant Human HERC3 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      13 kDa
    • Amino acids

      232 to 358
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • HECT and RLD domain containing E3 ubiquitin protein ligase 3
    • HECT domain and RCC1 like domain containing protein 3
    • Hect domain and RLD 3
    • HERC 3
    • KIAA0032
    • Probable E3 ubiquitin protein ligase HERC3
    see all
  • Relevance

    HERC3 (Hect domain and RLD 3) belongs to the HERC family of ubiquitin ligases which contain a HECT domain and at least 1 RCC1-like domain (RLD). E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. The RLD domain is predicted to act as a guanine nucleotide exchange factor for small G proteins.
  • Cellular localization

    Cytoplasmic. Cytoplasmic vesicle. Note: Also found in vesicular-like structures.

References

ab127435 has not yet been referenced specifically in any publications.

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