Overview

  • Product name

    Recombinant Human HERC6 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      32 kDa
    • Amino acids

      713 to 983
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127390 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration.

General Info

  • Alternative names

    • EC 6.3.2.
    • FLJ20637
    • HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
    • HECT domain and RCC1 like domain containing protein 6
    • HECT domain and RCC1-like domain 6
    • HECT domain and RCC1-like domain-containing protein 6
    • Hect domain and RLD 6
    • HERC 6
    • HERC6
    • HERC6_HUMAN
    • Potential ubiquitin ligase
    • Probable E3 ubiquitin protein ligase HERC6
    • Probable E3 ubiquitin-protein ligase HERC6
    see all
  • Function

    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
  • Tissue specificity

    Detected in brain, heart, placenta and testis.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
    Contains 5 RCC1 repeats.
  • Developmental stage

    Expressed in fetal brain.
  • Cellular localization

    Cytoplasm > cytosol.
  • Information by UniProt

References

ab127390 has not yet been referenced specifically in any publications.

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