Overview

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      12 kDa
    • Amino acids

      59 to 163
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration

General Info

  • Alternative names

    • 1190005L05Rik
    • HINT-2
    • HINT-3
    • HINT2
    • HINT2_HUMAN
    • histidine triad nucleotide binding protein 2
    • Histidine triad nucleotide-binding protein 2
    • HIT-17
    • HIT-17kDa
    • mitochondrial
    • PKCI-1-related HIT protein
    • Protein kinase C inhibitor 2
    see all
  • Function

    Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity.
  • Tissue specificity

    High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.
  • Sequence similarities

    Belongs to the HINT family.
    Contains 1 HIT domain.
  • Domain

    The histidine triad, also called HIT motif, forms part of the binding loop for the alpha-phosphate of purine mononucleotide.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt

References

ab127317 has not yet been referenced specifically in any publications.

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