Description

  • Product name

    Recombinant human HIPK4 protein
    See all HIPK4 proteins and peptides
  • Biological activity

    Specific Activity: 202 nmol /min/mg as determined in kinase assay.
  • Expression system

    Baculovirus infected Sf9 cells
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      Purity> 70% by densitometry.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab69925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.87% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • HIPK 4
    • HIPK4
    • HIPK4_HUMAN
    • Homeodomain interacting protein kinase 4
    • Homeodomain-interacting protein kinase 4
    see all
  • Function

    Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Autophosphorylated.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • The specific activity of HIPK4 (ab69925) was determined to be 175 nmol/min/mg as per activity assay protocol
  • SDS PAGE analysis of ab69925
  • SDS PAGE analysis of ab69925

References

ab69925 has not yet been referenced specifically in any publications.

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