Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSTKADHMG SYGPAFYQSY GASGQFTHEF DEEQLFSVDL KKSEAVWRLP EFGDFARFDP QGGLAGIAAI KAHLDILVER SNRSRAINVP PRVTVLPKSR VELGQPNILI CIVDNIFPPV INITWLRNGQ TVTEGVAQTS FYSQPDHLFR KFHYLPFVPS AEDVYDCQVE HWGLDAPLLR HWELQVPIPP PDAME
    • Molecular weight
      24 kDa including tags
    • Amino acids
      26 to 217
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167908 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    >90% by SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituents: 2.4% Urea, 10% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • HLA class II histocompatibility antigen, DO alpha chain precursor
    • HLA D0 alpha
    • HLA DNA
    • HLA DZA
    • HLADZ
    • Lymphocyte antigen
    • Major histocompatibility complex, class II, DN alpha
    • Major histocompatibility complex, class II, DO alpha
    • MHC class II antigen DOA
    • MHC DN alpha
    • MHC DZ alpha
    see all
  • Relevance
    HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
  • Cellular localization
    Cell Membrane; Single-pass type I membrane protein.

Images

  • 15% SDS-PAGE analysis of 3 µg ab167908.

References

ab167908 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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