Overview

  • Product name
    Recombinant Human HLA-DP protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPT GEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNN LNTLIQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNV TWLCNGEPVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDVYDCRVEHWG LDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRS GHDPRAQGPL
    • Amino acids
      1 to 260
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • DP(W3)
    • DP(W4)
    • HLA class II histocompatibility antigen DP alpha 1 chain
    • HLA class II histocompatibility antigen DP alpha chain
    • HLA DP1A
    • HLA DPA 1
    • HLA SB alpha chain
    • HLADP
    • HLADPA1
    • HLASB
    • HLASB histocompatibility type
    • Human MHC class II HLA SB alpha gene
    • Major histocompatibility complex class II DP alpha 1
    • MHC class II antigen
    • MHC class II DP3 alpha
    • MHC class II DPA1
    • MHC class II HLA DPA1 antigen
    • PLT1
    • Primed lymphocyte test 1
    see all
  • Relevance
    HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a vital role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells and macrophages). Within the DP molecule the alpha and beta chain contain the polymorphisms governing the peptide binding specificities, resulting in up to 4 different molecules.
  • Cellular localization
    Type I membrane protein; Cell Membrane, Endoplasmic reticulum and Golgi Apparatus

Images

  • ab158656 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158656 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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