Description

  • Product name

    Recombinant Human HMGCS1 protein
  • Purity

    > 80 % SDS-PAGE.
    ab201881 was purified by using conventional chromatography techniques.
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MGSMPGSLPL NAEACWPKDV GIVALEIYFP SQYVDQAELE KYDGVDAGKY TIGLGQAKMG FCTDREDINS LCMTVVQNLM ERNNLSYDCI GRLEVGTETI IDKSKSVKTN LMQLFEESGN TDIEGIDTTN ACYGGTAAVF NAVNWIESSS WDGRYALVVA GDIAVYATGN ARPTGGVGAV ALLIGPNAPL IFERGLRGTH MQHAYDFYKP DMLSEYPIVD GKLSIQCYLS ALDRCYSVYC KKIHAQWQKE GNDKDFTLND FGFMIFHSPY CKLVQKSLAR MLLNDFLNDQ NRDKNSIYSG LEAFGDVKLE DTYFDRDVEK AFMKASSELF SQKTKASLLV SNQNGNMYTS SVYGSLASVL AQYSPQQLAG KRIGVFSYGS GLAATLYSLK VTQDATPGSA LDKITASLCD LKSRLDSRTG VAPDVFAENM KLREDTHHLV NYIPQGSIDS LFEGTWYLVR VDEKHRRTYA RRPTPNDDTL DEGVGLVHSN IATEHIPSPA KKVPRLPATA AEPEAAVISN GEH
    • Predicted molecular weight

      60 kDa including tags
    • Amino acids

      1 to 520
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_001091742

Specifications

Our Abpromise guarantee covers the use of ab201881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 89% PBS, 10% Glycerol, 0.0154% DTT

General Info

  • Alternative names

    • 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble)
    • 3-hydroxy-3-methylglutaryl coenzyme A synthase
    • cytoplasmic
    • EC 2.3.3.10
    • HMCS1_HUMAN
    • HMG CoA synthase
    • HMG-CoA synthase
    • HMGCS
    • HMGCS1
    • Hydroxymethylglutaryl CoA synthase, cytoplasmic
    • Hydroxymethylglutaryl-CoA synthase
    • MGC90332
    see all
  • Function

    This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  • Pathway

    Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3.
  • Sequence similarities

    Belongs to the HMG-CoA synthase family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS PAGE analysis of ab201881 (3 µg).

References

ab201881 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab201881.
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