Overview

  • Product name

    Recombinant Human HNK-1ST protein (denatured)
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Sequence

      MGSSHHHHHH SSGLVPRGSH MTFKDPDVYS AKQEFLFLTT MPEVRKLPEE KHIPEELKPT GKELPDSQLV QPLVYMERLE LIRNVCRDDA LKNLSHTPVS KFVLDRIFVC DKHKILFCQT PKVGNTQWKK VLIVLNGAFS SIEEIPENVV HDHEKNGLPR LSSFSDAEIQ KRLKTYFKFF IVRDPFERLI SAFKDKFVHN PRFEPWYRHE IAPGIIRKYR RNRTETRGIQ FEDFVRYLGD PNHRWLDLQF GDHIIHWVTY VELCAPCEIM YSVIGHHETL EDDAPYILKE AGIDHLVSYP TIPPGITVYN RTKVEHYFLG ISKRDIRRLY ARFEGDFKLF GYQKPDFLLN
    • Molecular weight

      41 kDa including tags
    • Amino acids

      28 to 356
    • Tags

      His tag N-Terminus
    • Additional sequence information

      NP_004845.

Specifications

Our Abpromise guarantee covers the use of ab202629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 85 % SDS-PAGE.
    ab202629 was purified by conventional chromatography techniques.
  • Form

    Liquid
  • Additional notes

    Previously labelled as CHST10.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.0
    Constituents: 10% Glycerol, 0.32% Tris HCl

General Info

  • Alternative names

    • Carbohydrate sulfotransferase 10
    • CHST10
    • CHSTA_HUMAN
    • EC 2.8.2.-
    • HNK-1 sulfotransferase
    • HNK-1ST
    • HNK1ST
    • huHNK-1ST
    • MGC17148
    • OTTHUMP00000203188
    see all
  • Function

    Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
  • Tissue specificity

    In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues. In brain, it is expressed at higher level in the frontal lobe.
  • Sequence similarities

    Belongs to the sulfotransferase 2 family.
  • Cellular localization

    Golgi apparatus membrane.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab202629 (3μg).

References

ab202629 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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