Recombinant Human HNRNPM protein (Tagged) (ab226407)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human HNRNPM protein (Tagged) -
Purity
> 90 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
AAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKE KNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYV ELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGE HARRAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGR LGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTF EQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGL GGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEG PFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGI ERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMG SGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPI DRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRM ATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALG AGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARK ACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFES PEVAERACRMMNGMKLSGREIDVRIDRNA -
Predicted molecular weight
93 kDa including tags -
Amino acids
2 to 730 -
Tags
His tag N-Terminus -
Additional sequence information
6xHis-SUMO tag at the N-terminus.
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab226407 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: 50% Glycerol (glycerin, glycerine), Tris buffer
General Info
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Alternative names
- CEA receptor
- CEAR
- Heterogeneous nuclear ribonucleoprotein M
see all -
Function
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. -
Sequence similarities
Contains 3 RRM (RNA recognition motif) domains. -
Post-translational
modificationsSumoylated. -
Cellular localization
Nucleus > nucleolus. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab226407 has been referenced in 1 publication.
- Marzec KA et al. SILAC kinase screen identifies potential MASTL substrates. Sci Rep 12:10568 (2022). PubMed: 35732702