For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome
Recombinant Human HRSP12 protein
Full length protein
Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
- 14.5 kDa translational inhibitor protein
- 2-iminobutanoate/2-iminopropanoate deaminase
- Heat responsive protein 12
Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA.
Hepatocytes and renal distal tubular epithelial cells. Only weak expression in other tissues.
Belongs to the RutC family.
Up-regulated during cellular differentiation.
Cytoplasm. Nucleus. Mostly cytoplasmic but, in less differentiated cells occasionally nuclear.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"